累计获批国家发明专利、PCT 专利 10 项,实现千万元成果转化。同时兼任国内多家国家级眼科、遗传、罕见病专业委员会核心职务,在遗传性眼病基础研究、临床诊疗与新药产业化领域造诣深厚,行业影响力突出。
Prof. Liping Yang, Peking University Third Hospital, is a global leader in gene therapy for inherited retinal dystrophies (IRDs). With a Ph.D. from Peking University, she pioneered ZVS101e, the world’s first gene replacement therapy for Bietti crystalline corneoretinal dystrophy (BCD). Launched a clinical trial in 2021, ZVS101e earned US FDA Orphan Drug Designation, China NMPA Breakthrough Therapy status, and US FDA Regenerative Medicine Advanced Therapy certification. Now in Phase III trials, it has shown significant efficacy in more than 60 patients, with related work published in Molecular Therapy, Nature Communications, Progress in Retinal and Eye Research and Signal Transduction and Targeted Therapy. Her team’s RHO gene editing research for retinitis pigmentosa, published in eLife (2023), further showcases her innovation. With over 20 high-impact publications, she has set global standards for IRDs treatment and gene therapy.
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| 日期 | 时间 | 会场 | Session | 角色 | 讲题 |
|---|---|---|---|---|---|
| 2026-05-30 | 15:00-15:15 | 分会场4(二层,N210会议室) |
2026中国眼谷国际眼健康科技创新与产业发展会议 |
讲者 | 结晶样视网膜变性基因治疗药物研发及转化 |